Improvement of the bio-functional properties of TiO2 nanotubes
PBN-AR
Instytucja
Wydział Inżynierii Materiałowej (Politechnika Warszawska)
Źródłowe zdarzenia ewaluacyjne
Informacje podstawowe
Główny język publikacji
en
Czasopismo
Applied Surface Science
ISSN
0169-4332
EISSN
Wydawca
Elsevier BV - North-Holland
DOI
Rok publikacji
2016
Numer zeszytu
388
Strony od-do
775-785
Numer tomu
Identyfikator DOI
Liczba arkuszy
0.5
Słowa kluczowe
en
Titanium oxide nanotubes (TiO2NT), Surface characterization methods, Bone forming ability, Bioactivity, Antibacterial properties
Streszczenia
Język
en
Treść
Titanium oxide nanotubes with diameters from ca. 40–120 nm fabricated by the anodic oxidation of Ti ata constant voltage (10–28 V) were investigated to identify factors improving their bio-functional prop-erties. Prepared substrates were subsequently annealed at 450◦C and 650◦C to obtain nanotubes havinga crystalline structure, and were then examined by SEM, XRD, XPS, BET and contact angle measure-ment techniques. The thermally stabilized surfaces were subjected to bidirectional functionalization: bydeposition of a thin layer of Ca-P and by loading with silver nanoparticles. Three factors were found topromote the proliferation of osteoblast (U2OS) cells: a larger nanotube diameter, a higher annealing tem-perature, and the presence of a thin Ca-P layer. Differentiation of these cells (by ALP test) was stimulatedby a higher (650◦C) nanotube annealing temperature, but not by a thin Ca-P layer. The TiO2nanotubes-modified samples exhibited noticeable antibacterial properties. Moreover, the additional deposition ofAg nanoparticles almost completely inhibited the survivability of S. epidermidis cells beyond 3 h of con-tact. In conclusion, TiO2nanotubes-modified surfaces exhibit distinct bone forming ability and significantantibacterial properties, and can be easily functionalized by a thin Ca-P layer or nano-Ag deposition forfurther improvement of the above functionalities.
Inne
System-identifier
WUT6ff8a7ac2a2e476889cf93cacf74453f
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