Hypertension in patients with Alzheimer's disease—prevalence, characteristics, and impact on clinical outcome. Experience of one neurology center in Poland
PBN-AR
Instytucja
Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk
Źródłowe zdarzenia ewaluacyjne
Informacje podstawowe
Główny język publikacji
en
Czasopismo
Journal of the American Society of Hypertension
ISSN
1933-1711
EISSN
Wydawca
ELSEVIER SCIENCE INC
DOI
URL
Rok publikacji
2015
Numer zeszytu
9
Strony od-do
711-724
Numer tomu
9
Identyfikator DOI
Liczba arkuszy
1,42
Słowa kluczowe
en
Alzheimer's disease
dementia
hypertension
mortality
Streszczenia
Język
en
Treść
The aim of the study was to evaluate hypertension (HT) prevalence, characteristics, and impact on clinical outcome in patients with Alzheimer's disease (AD). We evaluated 701 patients with AD (249 males, 452 females, and mean age 74.9 ± 7.5 years). As a group representing general population matched with regard to age, education level, and place of residence, we included 762 subjects (438 males, 324 females, and mean age 74.7 ± 4.4 years) from the Polish National Multicenter Health Survey (WOBASZ) studies. The patients with AD were characterized by lower systolic blood pressure (BP) and diastolic BP values (134 ± 21 vs. 151 ± 23 mm Hg, P < .001 and 77 ± 11 vs. 86 ± 12 mm Hg, P < .001, respectively) as well as lower HT prevalence (66% vs. 78.6%, P < .001) compared with the WOBASZ group. In long-term follow-up of AD group, HT and BP levels were not associated with the decline in cognitive functions nor the increased risk of death. Patients with AD were characterized by lower prevalence of HT and other vascular risk factors. BP levels and HT had no impact on clinical outcome.
Cechy publikacji
ORIGINAL_ARTICLE
Inne
System-identifier
691478
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