Disease activity, quality of life, and indirect costs of ulcerative colitis in Poland.
PBN-AR
Instytucja
Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie
Źródłowe zdarzenia ewaluacyjne
Informacje podstawowe
Główny język publikacji
angielski
Czasopismo
Przegląd Gastroenterologiczny (15pkt w roku publikacji)
ISSN
1895-5770
EISSN
1897-4317
Wydawca
TERMEDIA PUBLISHING HOUSE LTD
DOI
Rok publikacji
2017
Numer zeszytu
1
Strony od-do
60-65
Numer tomu
12
Identyfikator DOI
Liczba arkuszy
0,27
Słowa kluczowe
angielski
indirect costs;
productivity loss;
quality of life;
ulcerative colitis
Open access
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Język
angielski
Treść
INTRODUCTION: Ulcerative colitis (UC) require expensive, lifelong treatment, which generates huge direct costs and has a significant impact on the quality of life, especially in the active state of the disease. AIM: To assess the indirect costs, health-related quality of life, and clinical characteristics of patients with UC in Poland. Additionally, we investigated the association between activity of UC and productivity loss of patients in a Polish setting. MATERIAL AND METHODS: A questionnaire survey was conducted using the Patient Simple Clinical Colitis Activity Index (P-SCCAI) to assess disease activity, as well as the modified Work Productivity and Activity Impairment Questionnaire to assess productivity loss. The quality of life was presented as utility calculated with the EQ-5D-3L questionnaire. Indirect costs were assessed with the Human Capital Approach and were expressed in Polish zlotys (PLN) as well as in euros (€). Correlations were presented using the Spearman coefficient. RESULTS: We performed our analysis based on 202 full questionnaires collected. Mean patient age and age at disease onset were 33.14 years (standard deviation (SD): 9.90) and 26.35 years (SD: 8.89), respectively. The mean P-SCCAI score in the analysed group of patients was 8.26, and the mean utility was 0.8651. Average and median annual indirect costs per working person were €2043 and €1389 (8543 PLN and 5808 PLN), respectively, calculated using the gross domestic product, as well as €4791 and €3257 (20,026 PLN and 13,615 PLN), respectively, calculated using the gross value added. Total productivity loss was significantly correlated with the disease activity. CONCLUSIONS: Ulcerative colitis causes a decrease in the quality of life as well as patients' productivity loss associated with both absenteeism and with presenteeism.
Cechy publikacji
Original paper
Inne
System-identifier
PX-59a83fd7d5de34c2c3c9c011
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