Silver nanoparticles as an alternative strategy against bacterial biofilms
PBN-AR
Instytucja
Wydział Biologii (Uniwersytet Warszawski)
Informacje podstawowe
Główny język publikacji
en
Czasopismo
Acta Biochimica Polonica
ISSN
0001-527X
EISSN
1734-154X
Wydawca
Polskie Towarzystwo Biochemiczne i Komitet Biochemii i Biofizyki PAN
DOI
Rok publikacji
2013
Numer zeszytu
4
Strony od-do
523-530
Numer tomu
60
Link do pełnego tekstu
Identyfikator DOI
Liczba arkuszy
Autorzy
Słowa kluczowe
en
biofilm
antibacterial
silver nanoparticles
Streszczenia
Język
en
Treść
Biofilms are complex bacterial communities that resist the action of antibiotics and the human immune system. Bacteria within biofilms are the cause of numerous, almost impossible to eradicate, persistent infections. Biofilms can form on many medical devices and implants, and so have an enormous impact on medicine. Due to the lack of effective anti-biofilm antibiotics, novel alternative compounds or strategies are urgently required. This review describes some of the latest approaches in the field of biofilm treatment. New anti-biofilm technologies target different stages in the biofilm formation process. Some act to modify the colonized biomaterials to make them resistant to biofilm formation. One potentially important candidate treatment uses silver nanoparticles that show anti-bacterial and anti-biofilm activity. The biological action of nano-silver is complex and seems to involve a number of pathways. However, there have been few reports on the anti-biofilm activity of silver nanoparticles and the precise mechanism underlying their action remains unresolved. Here, we describe some anti-biofilm approaches employing AgNPs and consider the challenges and problems that need to be addressed in order to make silver nanoparticles a part of an effective anti-biofilm strategy.
Cechy publikacji
REVIEW_ARTICLE
Inne
System-identifier
498072