Acute respiratory distress syndrome (ARDS) in the course of influenza A/H1N1v infection - genetic aspects
PBN-AR
Instytucja
Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk
Informacje podstawowe
Główny język publikacji
en
Czasopismo
Annals of Agricultural and Environmental Medicine
ISSN
1232-1966
EISSN
1898-2263
Wydawca
Institute of Rural Health
DOI
Rok publikacji
2013
Numer zeszytu
4
Strony od-do
711-714
Numer tomu
20
Identyfikator DOI
Liczba arkuszy
0,57
Słowa kluczowe
en
A/H1N1v influenza
complications
respiratory failure
MSSCP genotyping
Streszczenia
Język
en
Treść
Influenza is a contagious respiratory disease caused by viruses belonging to the family Ortomyxoviridae. Among the influenza viruses type A, B and C, the A type virus shows the most pathogenic potential. Its surface receptor glycoproteins, hemagglutinin (HA) and neuraminidase (NA), are characterized by high antigenic variation, thus a host organism cannot develop permanent resistance. The case is described of a male patient with severe acute respiratory distress syndrome in the course of influenza A/N1H1v infection, confirmed by virological molecular analysis. During diagnostic procedures based on the MSSCP genotyping it was observed that the WHO recommended RT-PCR kits and/or procedure of sample collection from patients for molecular investigation could lead to false positive A/H1N1 pandemic strain detection because of the co-amplification during the RT-PCR fragments of the human genonne.
Cechy publikacji
ORIGINAL_ARTICLE
Inne
System-identifier
597921