Język
en
Treść
7-Methylguanosine (m7G) nucleotides labelled with acetylpyrene
(AcPy) were synthesized as fluorescent mRNA 5’ end (cap) analogues.
The unique fluorescent properties of m7G–AcPy conjugates,
different from G–AcPy, can be applied to studying various
mRNA cap-related processes including the evaluation of putative
inhibitors of DcpS enzyme—a therapeutic target in neuromuscular
diseases.
