Changes in the Genetic Variance and Heritability of the Body Mass Index and Skinfolds among Polish Twins Aged 8–18 Years
PBN-AR
Instytucja
Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk
Informacje podstawowe
Główny język publikacji
angielski
Czasopismo
COLLEGIUM ANTROPOLOGICUM
ISSN
0350-6134
EISSN
Wydawca
COLLEGIUM ANTROPOLOGICUM
DOI
URL
Rok publikacji
2013
Numer zeszytu
2
Strony od-do
343-50
Numer tomu
37
Identyfikator DOI
Liczba arkuszy
Autorzy
Pozostali autorzy
+ 1
Słowa kluczowe
angielski
adiposity
twin studies
genetic variation
longitudinal studies
youth
Open access
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Inne
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Inna
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Streszczenia
Język
angielski
Treść
Body Mass Index (BMI) and skinfolds are common indicators of adiposity. Many studies have shown relationships between the BMI in childhood and adolescence and the BMI in adulthood. Similar correlations were observed for the skinfolds, although they tend to be lower. The aim of this study was to estimate changes with age in the genetic variance and heritability of the BMI and skinfolds among Polish twins born between 1959 and 1965. Observations involved male and female monozygotic (MZ) and dizygotic (DZ) twins, who were measured annually between 8 and 18 years of age. Body Mass Index and skinfold thicknesses at the triceps (TSF), subscapular (SSF) and suprailiac (SIF) sites were measured. Genetic variance and heritability were estimated for individual skinfold thicknesses, the sum of three skinfolds (SUMSF) and BM, separately by age classes for both sexes. Intraclass correlations were significantly higher for MZ twins than for DZ twins in both sexes and across all ages. Heritability estimates were significant for all indicators of adiposity, but varied with age and had different ranges for boys and girls. Estimates of genetic variance were significant for all indicators of adiposity and were higher for girls than for boys.
Cechy publikacji
artykuł oryginalny
Inne
System-identifier
PX-58ab1c8bd5de313d3de0be07