Preparation and characterization of ZnO-PMMA resin nanocomposites for denture bases
PBN-AR
Instytucja
Instytut Wysokich Ciśnień Polskiej Akademii Nauk
Informacje podstawowe
Główny język publikacji
angielski
Czasopismo
Acta of Bioengineering and Biomechanics
ISSN
1509-409X
EISSN
2450-6303
Wydawca
Wydział Mechaniczny Politechnika Wrocławska
Rok publikacji
2016
Numer zeszytu
2
Strony od-do
31-41
Numer tomu
18
Identyfikator DOI
Liczba arkuszy
1,1
Słowa kluczowe
angielski
ZnO nanoparticles
Candida albicans
acrylic resins
Open access
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Inne
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Inna
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Data udostępnienia w sposób otwarty
Streszczenia
Język
angielski
Treść
The aim of the paper was to investigate the antifungal activity of zinc oxide nanoparticles (ZnONPs) against Candida albicans. Some attempts have been made to find out the best way to introduce ZnONPs into polymethyl methacrylate (PMMA) resin material and to determine some parameters of a newly formed composite. Material and methods: Zinc oxide nanoparticles were manufactured and their basic physical parameters were determined (average particle size, density, specific surface area). Minimal inhibitory concentration (MIC) of ZnONPs was determined for the Candida albicans standard strain. The average size of ZnO conglomerates in the monomer solution of PMMA resin was measured using a dynamic light scattering instrument. PMMA resin samples with incorporated ZnONPs were produced. The morphology of nanopowder and the newly formed composite was examined under a scanning electron microscope (SEM). In addition, the roughness parameter of PMMA resin material was investigated before and after ZnONPs modification. Results: Nanopowder with the average particle size of 30 nm, density of 5.24 g/cm3 and surface area of 39 m2 /g was obtained. MIC was determined at the level of 0.75 mg/mL. The average size of ZnO conglomerates in the monomer solution of acrylic resin dropped by 11 times after ultrasound activation. SEM examination of a newly formed composite showed a successful introduction of ZnONPs confirmed by the energy dispersive X-ray spectroscopy (EDS) analysis. There were no statistically significant differences in the biomaterial roughness before and after the modification of ZnONPs. Conclusion: Zinc oxide nanoparticles were successfully incorporated into acrylic resin used for the production of denture bases. The presence of nanoparticles with sizes below 100 nm was confirmed. Nevertheless a newly created composite needs to be further investigated to improve its homogeneity, and to check its microbiological properties, strength and biocompatibility prior to its possible clinical use.
Inne
System-identifier
PX-58b41b1dd5deeb14a5fd8534
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