Inspired by Nature: The Use of Plant-derived Substrate/Enzyme Combinations to Generate Antimicrobial Activity in situ
PBN-AR
Instytucja
Wydział Chemiczny (Politechnika Gdańska)
Informacje podstawowe
Główny język publikacji
ENG
Czasopismo
Natural Product Communications
ISSN
1934-578X
EISSN
Wydawca
DOI
URL
Rok publikacji
2015
Numer zeszytu
10
Strony od-do
1733-1738
Numer tomu
10
Link do pełnego tekstu
Identyfikator DOI
Liczba arkuszy
Słowa kluczowe
ALLIIN
ALLIINASE
ANTIMICROBIAL ACTIVITY
BINARY SYSTEM
Streszczenia
Język
Treść
The last decade has witnessed a renewed interest in antimicrobial agents. Plants have received particular attention and frequently rely on the spontaneous enzymatic conversion of an inactive precursor to an active agent. Such two-component substrate/enzyme defence systems can be reconstituted ex vivo. Here, the alliin/alliinase system from garlic seems to be rather effective against Saccharomyces cerevisiae, whilst the glucosinolate/myrosinase system from mustard appears to be more active against certain bacteria. Studies with myrosinase also confirm that enzyme and substrate can be added sequentially. Ultimately, such binary systems hold considerable promise and may be employed in a medical or agricultural context.
Inne
System-identifier
133980