A new division of bacterial UvrA homologues
PBN-AR
Instytucja
Wydział Chemiczny (Politechnika Gdańska)
Informacje podstawowe
Główny język publikacji
ENG
Czasopismo
BioTechnologia
ISSN
0860-7796
EISSN
Wydawca
DOI
URL
Rok publikacji
2013
Numer zeszytu
1
Strony od-do
54-56
Numer tomu
94
Identyfikator DOI
Liczba arkuszy
Słowa kluczowe
UVRA BACTERIA
Streszczenia
Język
Treść
The UvrA protein is a DNA-binding and damage-recognition enzyme which participates in the prokaryotic type nucleotide excision repair (NER) pathway. It has recently been noted that some bacterial genomes comprise additional uvrA genes which encode five distinct types of UvrA homologue. We investigated the sequences of over 2400 bacterial genomes and found 130 examples of bacteria containing uvrA 2 genes. The sequence analyses conducted on these UvrA homologues revealed that the previously established division of UvrA proteins might be based on some incorrect assumptions. In this paper, we present the reasons for our creation of a new division of UvrA homologues and a description of the four UvrA classes we have created.
Inne
System-identifier
126842