Knitting for heart valve tissue engineering
PBN-AR
Instytucja
Instytut Technologii Bezpieczeństwa MORATEX
Informacje podstawowe
Główny język publikacji
en
Czasopismo
Global Cardiology Science and Practice
ISSN
2305-7823
EISSN
brak
Wydawca
Magdi Yacoub Institute
DOI
Rok publikacji
2016
Numer zeszytu
3
Strony od-do
1-33
Numer tomu
2016
Identyfikator DOI
Liczba arkuszy
2,4
Autorzy
Pozostali autorzy
+ 5
Słowa kluczowe
en
knitting
heart valve
tissue engineering
cell growth
deposition
extracellular matrix
Streszczenia
Język
en
Treść
Knitting is a versatile technology which offers a large portfolio of products and solutions of interest in heart valve (HV) tissue engineering (TE). One of the main advantages of knitting is its ability to construct complex shapes and structures by precisely assembling the yarns in the desired position. With this in mind, knitting could be employed to construct a HV scaffold that closely resembles the authentic valve. This has the potential to reproduce the anisotropic structure that is characteristic of the heart valve with the yarns, in particular the 3-layered architecture of the leaflets. These yarns can provide oriented growth of cells lengthwise and consequently enable the deposition of extracellular matrix (ECM) proteins in an oriented manner. This technique, therefore, has a potential to provide a functional knitted scaffold, but to achieve that textile engineers need to gain a basic understanding of structural and mechanical aspects of the heart valve and in addition, tissue engineers must acquire the knowledge of tools and capacities that are essential in knitting technology. The aim of this review is to provide a platform to consolidate these two fields as well as to enable an efficient communication and cooperation among these two research areas.
Inne
System-identifier
PX-58aede0fd5dee5605828f59d
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