Are myelodysplastic syndromes underdiagnosed in Poland? A report by the Polish Adult Leukaemia Group
PBN-AR
Instytucja
Instytut Hematologii i Transfuzjologii
Informacje podstawowe
Główny język publikacji
angielski
Czasopismo
European Journal of Haematology (25pkt w roku publikacji)
ISSN
0902-4441
EISSN
1600-0609
Wydawca
WILEY-BLACKWELL
DOI
URL
Rok publikacji
2017
Numer zeszytu
2
Strony od-do
154-159
Numer tomu
98
Identyfikator DOI
Liczba arkuszy
Streszczenia
Język
angielski
Treść
The epidemiology of myelodysplastic syndromes (MDS) differs among countries. Here, we present the first epidemiological indices determined for Poland. Methods Twenty‐one haematological centres participated in the study. Patients diagnosed with MDS and acute myeloid leukaemia (AML) with 20–29% blasts were enrolled. Data collection was conducted for strictly predefined period. Results The overall crude incidence rate for all MDS subtypes was 1.95 (95% CI, 1.81–2.09) per 100 000 person‐years: 2.46 (95% CI, 2.24–2.69) for males and 1.47 (95% CI, 1.31–1.65) for females; after excluding AML cases, the indices were as follows: 2.35 (95% CI, 2.08–2.66) for males and 1.27 (95% CI, 1.08–1.5) for females. Prevalence rate was 6.2 per 100 000 persons (95% CI, 5.96–6.45), that is 6.86 (95% CI, 6.49–7.24) for males and 5.58 (95% CI, 5.26–5.92) for females. Both incidence and prevalence increased with increasing age. The most frequently diagnosed MDS subtype was refractory cytopenia with multilineage dysplasia (RCMD), responsible for 30.3% of all newly diagnosed MDSs. Conclusions RCMD is the most frequent MDS subtype in Poland. Incidence and prevalence indices are lower than those reported for other populations, which probably results from inadequate diagnosis of potential cases of this disease.
Cechy publikacji
discipline:Medycyna
discipline:Medicine
Original article
Original article presents the results of original research or experiment.
Oryginalny artykuł naukowy
Oryginalny artykuł naukowy przedstawia rezultaty oryginalnych badań naukowych lub eksperymentu.
Inne
System-identifier
EX-5ab1005ad5defde9ca771501
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