Influence of the Al content on the: In vitro bioactivity and biocompatibility of PVD Ti1- xAlxN coatings for orthopaedic applications
PBN-AR
Instytucja
Centrum Nanobiomedyczne (Uniwersytet im. Adama Mickiewicza w Poznaniu)
Informacje podstawowe
Główny język publikacji
en
Czasopismo
RSC Advances
ISSN
2046-2069
EISSN
Wydawca
DOI
URL
Rok publikacji
2016
Numer zeszytu
65
Strony od-do
60756-60764
Numer tomu
6
Identyfikator DOI
Liczba arkuszy
Słowa kluczowe
en
Aluminum coatings
Bioactivity
Biocompatibility
Coatings
Corrosion protection
Corrosion resistance
Cytotoxicity
Magnetrons
Medical applications
Phosphate minerals
Stainless steel
Titanium nitride
X ray photoelectron spectroscopy
Anti-corrosive properties
Biomedical applications
Chemical compositions
Lactate dehydrogenase
Magnetron co-sputtering
Orthopaedic applications
Simulated body fluids
Titanium aluminium nitride
Aluminum
Streszczenia
Język
en
Treść
Titanium aluminium nitride (Ti1-xAlxN) coatings are utilized in industrial applications because of their excellent tribological and anticorrosive properties. Recently these coatings have been proposed for biomedical applications. In this paper, the biocompatibility and bioactivity of Ti1-xAlxN coatings, having various aluminium contents, x, deposited on AISI 304SS stainless steel, have been studied. Coatings were synthesized by magnetron co-sputtering by varying the power applied to the aluminium target. Morphology, chemical composition and microstructure were studied by SEM, AFM, XPS and XRD. Biocompatibility was assessed by measuring haemolytic and cytotoxic characteristics. Haemolysis was measured following the ASTM F756 norm. The in vitro cytotoxicity was assessed with human osteoblasts by means of the lactate dehydrogenase (LDH) release assay. Bioactivity was measured by soaking the samples in a simulated body fluid (SBF) and analysing the surfaces by XPS, XRD and SEM. It was found that all the Ti1-xAlxN coatings exhibited good biocompatibility and bioactivity, precipitating hydroxyapatite and monetite. The aluminium content in the Ti1-xAlxN coatings increases the quantity of calcium and phosphates groups precipitated in the beginning of the process, but it was also observed an influence of the roughness in the quantity of apatite precipitated after 1 month of immersion in SBF. The coating with x = 0.69 exhibited the higher bioactivity. © 2016 The Royal Society of Chemistry.
Cechy publikacji
Original article
Original article presents the results of original research or experiment.
Oryginalny artykuł naukowy
Oryginalny artykuł naukowy przedstawia rezultaty oryginalnych badań naukowych lub eksperymentu.
Inne
System-identifier
PBN-R:873951
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