Structure and hemocompatibility of nanocrystalline titanium nitride produced under glow-discharge conditions.
PBN-AR
Instytucja
Instytut "Pomnik - Centrum Zdrowia Dziecka"
Informacje podstawowe
Główny język publikacji
en
Czasopismo
Applied Surface Science (35pkt w roku publikacji)
ISSN
0169-4332
EISSN
1873-5584
Wydawca
DOI
URL
Rok publikacji
2018
Numer zeszytu
April 2018
Strony od-do
382-390
Numer tomu
436
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Pozostali autorzy
+ 3
Słowa kluczowe
en
nitrided surface layer
glow-discharge nitriding
nanotopography
hemocompatiblity
Streszczenia
Język
angielski
Treść
Significant efforts are being made towards developing novel antithrombotic materials. The purpose of the presented study was to characterize two variants of nitrided surface layers produced on alloy Ti-6Al-4V in different areas of low-temperature plasma – at the plasma potential (TiNp) or at the cathode potential (TiNc). The layers were characterized in terms of their microstructure, surface topography and wettability, and platelet response to the environment of different pH. The produced layers were of the TiN + Ti2N + αTiN-type, but the layer produced at the plasma potential was thinner, smoother and had lower surface free energy compared with that produced at the cathode potential. Biological evaluation demonstrated more fibrinogen buildup, less platelet adhesion and aggregation, and fewer strongly activated platelets on the TiNp surface compared with those parameters on the TiNc surface and on the titanium alloy in its initial state. Interestingly, both surface types were significantly resistant to fibrinogen adsorption and platelet adhesion in the environment of lower pH. In conclusion, the nitrided surface layer produced at the plasma potential is a promising material and this basic information is critical for further development of hemocompatible materials.
Cechy publikacji
original-article
Inne
System-identifier
0000016880
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