Biotechnological applications of bacteriophages: State of the art.
PBN-AR
Instytucja
Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk
Informacje podstawowe
Główny język publikacji
angielski
Czasopismo
MICROBIOLOGICAL RESEARCH (25pkt w roku publikacji)
ISSN
0944-5013
EISSN
Wydawca
ELSEVIER GMBH, URBAN & FISCHER VERLAG
DOI
URL
Rok publikacji
2018
Numer zeszytu
Strony od-do
38-58
Numer tomu
212-213
Identyfikator DOI
Liczba arkuszy
Autorzy
(liczba autorów: 8)
Pozostali autorzy
+ 7
Słowa kluczowe
angielski
Bacterial biosensing
Bacteriophages
Biofilm control
Corrosion control
Food biopreservation and safety
Gene delivery
Phage display
Phage therapy
Structural and functional stabilization
Surface disinfection
Vaccine carriers
Streszczenia
Język
angielski
Treść
Bacteriophage particles are the most abundant biological entities on our planet, infecting specific bacterial hosts in every known environment and being major drivers of bacterial adaptive evolution. The study of bacteriophage particles potentially sheds light on the development of new biotechnology products. Bacteriophage therapy, although not new, makes use of strictly lytic phage particles as an alternative in the antimicrobial treatment of resistant bacterial infections and is being rediscovered as a safe method due to the fact that these biological entities devoid of any metabolic machinery do not have affinity to eukaryotic cells. Furthermore, bacteriophage-based vaccination is emerging as one of the most promising preventive strategies. This review paper discusses the biological nature of bacteriophage particles, their mode(s) of action and potential exploitation in modern biotechnology. Topics covered in detail include the potential of bacteriophage particles in human infections (bacteriophage therapy), nanocages for gene delivery, food biopreservation and safety, biocontrol of plant pathogens, phage display, bacterial biosensing devices, vaccines and vaccine carriers, biofilm and bacterial growth control, surface disinfection, corrosion control, together with structural and functional stabilization issues.
Cechy publikacji
artykuł przeglądowy
Inne
System-identifier
PX-5b5f05f9d5de797eeee9070e
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