Acute-on-chronic hepatitis. A case report of autoimmune hepatitis/primary sclerosing cholangitis/ulcerative colitis overlap syndrome in a 15-year-old patient.
PBN-AR
Instytucja
Instytut "Pomnik - Centrum Zdrowia Dziecka"
Informacje podstawowe
Główny język publikacji
en
Czasopismo
Clinical and Experimental Hepatology (7pkt w roku publikacji)
ISSN
2392-1099
EISSN
2449-8238
Wydawca
TERMEDIA PUBLISHING HOUSE LTD
DOI
Rok publikacji
2017
Numer zeszytu
1
Strony od-do
28-32
Numer tomu
3
Link do pełnego tekstu
Identyfikator DOI
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Słowa kluczowe
en
children
liver transplantation
ACLF
Streszczenia
Język
angielski
Treść
Acute-on-chronic liver failure (ACLF) is a disease in which a rapid deterioration of liver function occurs in patients with chronic liver disease, and is usually associated with a precipitating event. We present the case of a boy with autoimmune hepatitis/primary sclerosing cholangitis/ulcerative colitis (AIH/PSC/UC) overlap syndrome, in whom liver function was stable for 4.5 years of treatment. At 15 years of age the patient was hospitalized due to a deterioration of his general condition, severe abdominal pain, diarrhoea, vomiting and weight loss. There was also a rapid deterioration of liver function and a deterioration of renal function. Despite a wide spectrum of diagnostic examinations, no precipitating agent was found. After two episodes of massive bleeding from the gastrointestinal tract, the patient was transferred to the intensive care unit. The patient underwent a successful liver transplantation. ACLF can cause irreversible liver failure with a high mortality rate, which calls for liver transplantation.
Cechy publikacji
case-study
Inne
System-identifier
0000016251
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