Binary bioactive glass composite scaffolds for bone tissue engineering—Structure and mechanical properties in micro and nano scale. A preliminary study
PBN-AR
Instytucja
Instytut Podstawowych Problemów Techniki Polskiej Akademii Nauk
Informacje podstawowe
Główny język publikacji
EN
Czasopismo
Micron
ISSN
0968-4328
EISSN
Wydawca
DOI
Rok publikacji
2019
Numer zeszytu
Strony od-do
64-71
Numer tomu
119
Identyfikator DOI
Liczba arkuszy
Słowa kluczowe
EN
Bone tissue engineering
Composite scaffold
Bioactive glass
Mechanical properties
Streszczenia
Język
EN
Treść
Composite scaffolds of bioactive glass (SiO 2 -CaO) and bioresorbable polyesters: poly- l -lactic acid (PLLA) and polycaprolactone (PCL) were produced by polymer coating of porous foams. Their structure and mechanical properties were investigated in micro and nanoscale, by the means of scanning electron microscopy, PeakForce Quantitative Nanomechanical Property Mapping (PF-QNM) atomic force microscopy, micro-computed tomography and contact angle measurements. This is one of the first studies in which the nanomechanical properties (elastic modulus, adhesion) were measured and mapped simultaneously with topography imaging (PF-QNM AFM) for bioactive glass and bioactive glass – polymer coated scaffolds. Our findings show that polymer coated scaffolds had higher average roughness and lower stiffness in comparison to pure bioactive glass scaffolds. Such coating-dependent scaffold properties may promote different cells-scaffold interaction.
Cechy publikacji
original-article
Inne
System-identifier
6316
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