Characterization in vitro potency of biological active fractions of seeds, skins and flesh from selected Vitis vinifera L. cultivars and interspecific hybrids
PBN-AR
Instytucja
Wydział Biotechnologii i Nauk o Żywności (Uniwersytet Przyrodniczy we Wrocławiu)
Informacje podstawowe
Główny język publikacji
angielski
Czasopismo
Journal of Functional Foods
ISSN
1756-4646
EISSN
Wydawca
ELSEVIER SCIENCE BV
DOI
URL
Rok publikacji
2019
Numer zeszytu
Strony od-do
353-363
Numer tomu
56
Identyfikator DOI
Liczba arkuszy
0.5
Autorzy
Pozostali autorzy
+ 1
Słowa kluczowe
angielski
Antidiabetic and anticholinergic activity
Antioxidant capacity
Grapes
LC/MS-QTOF
Polyphenols
UPLC-PDA-FL
Streszczenia
Język
angielski
Treść
The aim of this study was to analyze phenolic compounds and in vitro biological activity of seeds, skins and flesh of V. vinifera cultivars and interspecific hybrids grown in Poland. Their phenolic profile was analyzed using LC-PDA-MS-QTOF and UPLC-PDA-FL and 48 compounds were identified, including nine phenolic acids, one stilbene, 12 anthocyanins, 10 flavonols and 16 flavan-3-ols. Seeds and red skins showed the highest antioxidant activity as measured with ABTS, FRAP and ORAC assays and on-line profiling by HPLC-PDA coupled with post-column derivatization with ABTS. Regarding anticholinergic activity, seeds and skins demonstrated higher AChE than BuChE activity, contrary to the flesh, where the ratio was reversed. In all seeds and most skins and flesh samples, inhibitory activity against α-glucosidase was higher than that against α-amylase. In conclusion, the investigated grape elements may be attractive components of functional foods and nutraceuticals, and seeds – being by-products of the wine industry – can be utilized.
Inne
System-identifier
UPWr6d66b03069704228ba34cb11d311e594
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